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Article

Association of CYP3A4/5 genotypes and expression with the survival of patients with neuroblastoma.

Molecular medicine reports - 1 Feb 2015

Darwish Mohamad H, Farah Roula A, Farhat Ghada N, Torbey Paul-Henri N, Ghandour Fatima A, Bejjani-Doueihy Noha A, Dhaini Hassan R

Abstract excerpt

Neuroblastoma (NB) is a rare pediatric disease in Lebanon for which poor prognosis remains a major challenge. Genetic polymorphism of genes coding for drug‑metabolizing enzymes may influence the response of a patient to chemotherapy. This study investigates a possible association between CYP3A4/5 polymorphism and expression levels and survival in NB patients. All patients with stage III and IV NB diagnosed...

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Share to Cytochrome P-450 CYP3A
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25370902
DOI: 10.3892/mmr.2014.2835

Genes

MYCN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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