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Article

Common genetic variations in cell cycle and DNA repair pathways associated with pediatric brain tumor susceptibility.

Oncotarget - 27 Sept 2016

Adel Fahmideh Maral, Lavebratt Catharina, Schüz Joachim, Röösli Martin, Tynes Tore, Grotzer Michael A, Johansen Christoffer, Kuehni Claudia E, Lannering Birgitta, Prochazka Michaela, Schmidt Lisbeth S, Feychting Maria

Abstract excerpt

Knowledge on the role of genetic polymorphisms in the etiology of pediatric brain tumors (PBTs) is limited. Therefore, we investigated the association between single nucleotide polymorphisms (SNPs), identified by candidate gene-association studies on adult brain tumors, and PBT risk.The study is based on the largest series of PBT cases to date. Saliva DNA from 245 cases and 489 controls, aged 7-19 years at...

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Identifiers

PMID: 27613841
DOI: 10.18632/oncotarget.11575
PMCID: PMC5325391

Genes

ATM
EGFR
EME1
ERCC1
XRCC1
XRCC4

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