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Article

The influence of COMT and ABCB1 gene polymorphisms on sufentanil analgesic effect for postoperative pain in children with fracture.

Medicine - 26 Apr 2024

Wang Hui, An Jianzhong, Zhong Shan, Qiao Shigang, Zhang Li, Zhao Longde, Wang Chen

Abstract excerpt

The aim of this observational study was to investigate the effects of catechol-O-methyltransferase (COMT) and ATP-binding cassette transporter B1 (ABCB1) gene polymorphisms on the postoperative analgesic effect of sufentanil in Chinese Han pediatric patients with fractures. A total of 185 pediatric patients who underwent fracture surgery were included. Polymerase chain reaction-restriction fragment length...

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Share to Analgesics, Opioid
Share to ATP Binding Cassette Transporter, Subfamily B

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Catechol O-Methyltransferase

Share to Child, Preschool

Share to Fractures, Bone

Share to Pain Measurement

Share to Pain, Postoperative

Share to Polymorphism, Genetic

Source

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Identifiers

PMID: 38669362
DOI: 10.1097/MD.0000000000037980
PMCID: PMC11049768

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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