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Article

COMT genetic variants and pain.

Drugs of today (Barcelona, Spain : 1998) - 1 Jun 2011

Belfer Inna, Segall S

Abstract excerpt

Catechol-O-methyltransferase (COMT) metabolizes catechol neurotransmitters dopamine, noradrenaline and adrenaline that are involved in various physiological functions including mood, cognition and stress response. Human pain is closely related to all these functions. The gene encoding the COMT enzyme (COMT) has functional polymorphisms that contribute to the interindividual variability in human pain phenotypes...

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Source

Identifiers

PMID: 21695287
DOI: 10.1358/dot.2011.47.6.1611895

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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The consequence of concomitantly present functional genetic variants for the identification of functional genotype-phenotype associations in pain.Semantic proximity Read ↗

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