Nicotinic Receptor Alpha-5 Subunit Gene Polymorphism is Associated With Heavy Smoking Under a Range of Nicotine Dosing Conditions.

doi:10.1093/ntr/ntae075

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Nicotinic Receptor Alpha-5 Subunit Gene Polymorphism is Associated With Heavy Smoking Under a Range of Nicotine Dosing Conditions.

Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco - 23 Sept 2024

Zuo Yantao, Rose Jed E, Davis James M, Behrens Kelsey A, Golaub Aisha A, Chandra Upasana U, Aarons Emily K, Morgan-Glover Janiece D, Mukhin Alexey G

Abstract excerpt

INTRODUCTION: This study aimed to assess the role of the rs16969968 variant of nicotinic receptor alpha-5 subunit in regulating smoking behavior and nicotine intake in response to nicotine manipulations among dependent smokers in a naturalistic environment. AIMS AND METHODS: Sixty-nine adults (19 females) smoking 10 or more cigarettes per day (CPD) were asked to complete four 2-week study phases during which they...

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PMID: 38654694
DOI: 10.1093/ntr/ntae075
PMCID: PMC11417125

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