Article
Nicotinic receptor gene variants influence susceptibility to heavy smoking.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Dec 2008
Stevens Victoria L, Bierut Laura J, Talbot Jeffrey T, Wang Jen C, Sun Juzhong, Hinrichs Anthony L, Thun Michael J, Goate Alison, Calle Eugenia E
Abstract excerpt
Heavy smoking is a strong predictor of nicotine dependence, which is a major impediment to smoking cessation. Although both heavy smoking and nicotine dependence are highly heritable, previous attempts to identify genes influencing these phenotypes have been largely unsuccessful until very recently. We studied 1,452 heavy smokers (defined as smoking at least 30 cigarettes per day for at least 5 years) and 1,395...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.