Association between CHRNA5 genetic variation at rs16969968 and brain reactivity to smoking images in nicotine dependent women.

doi:10.1016/j.drugalcdep.2011.06.009

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Article

Association between CHRNA5 genetic variation at rs16969968 and brain reactivity to smoking images in nicotine dependent women.

Drug and alcohol dependence - 1 Jan 2012

Janes Amy C, Smoller Jordan W, David Sean P, Frederick Blaise Deb, Haddad Stephen, Basu Aditi, Fava Maurizio, Evins A Eden, Kaufman Marc J

Abstract excerpt

BACKGROUND: Tobacco smoking is the leading preventable cause of death in the developed world. Identifying risk factors for smoking may lead to more effective treatments. Genome wide association studies revealed a relationship between development of nicotine dependence and a single-nucleotide polymorphism (SNP, rs16969968) of the nicotine acetylcholine receptor (nAChR) alpha-5 subunit gene (CHRNA5). The...

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Identifiers

PMID: 21764527
DOI: 10.1016/j.drugalcdep.2011.06.009
PMCID: PMC3203995

Genes

CHRNA5

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