Article
Genomic landscape of diploid and aneuploid microsatellite stable early onset colorectal cancer.
Scientific reports - 23 Apr 2024
Zhou Yumei, Chen Xianfeng, Chen Jun, Kendrick Conner D, Ramanathan Ramesh K, Graham Rondell P, Kossick Kimberlee F, Boardman Lisa A, Barrett Michael T
Abstract excerpt
Although colorectal cancer (CRC) remains the second leading cause of cancer-related death in the United States, the overall incidence and mortality from the disease have declined in recent decades. In contrast, there has been a steady increase in the incidence of CRC in individuals under 50 years of age. Hereditary syndromes contribute disproportionately to early onset CRC (EOCRC). These include microsatellite...
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