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The genomics of sporadic and hereditary colorectal cancer

31 Mar 2024

Abstract excerpt

Colorectal cancer (CRC) is a leading cause of cancer deaths worldwide. Over the past three decades, extensive efforts have sought to elucidate the genomic landscape of CRC. These studies reveal that CRC is highly heterogeneous at the molecular level, with different subtypes characterised by distinct somatic mutational profiles, epigenetic aberrations and transcriptomic signatures. This review summarises our...

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PMID: 38555871
DOI: 10.1308/rcsann.2024.0024

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