Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Germline Profiling and Molecular Characterization of Early Onset Metastatic Colorectal Cancer

19 Oct 2020

Abstract excerpt

Background Early onset colorectal cancer (EOCRC) is a heterogeneous colorectal cancer subtype with obvious hereditary tendencies and increasing incidence. We sought to determine the susceptibility genes and molecular characteristics of EOCRC. Methods 330 EO metastatic CRC (mCRC) (≤55 years) and 110 average-onset (AO) mCRC patients (>55 years) were enrolled. Capture-based targeted sequencing was performed on tumor...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to Colorectal Cancer Treatments and Studies
Share to Genetic factors in colorectal cancer

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33194656
DOI: 10.3389/fonc.2020.568911

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 17 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Germline Profiling and Molecular Characterization of Early Onset Metastatic Colorectal CancerPMID 33194656Read ↗

Molecular genetics of early-onset colorectal cancerSemantic proximity Read ↗

Genomic Landscapes of Early-Onset Versus Average-Onset Colorectal Cancer PopulationsSemantic proximity Read ↗

Molecular characteristics of early-onset compared with late-onset colorectal cancer: a case controlled study.Semantic proximity Read ↗

Mutational and co-mutational landscape of early onset colorectal cancer.Semantic proximity Read ↗

Molecular Heterogeneity in Early-Onset Colorectal Cancer: Pathway-Specific Insights in High-Risk PopulationsSemantic proximity Read ↗

Molecular Heterogeneity in Early-Onset Colorectal Cancer: Pathway-Specific Insights in High-Risk PopulationsSemantic proximity Read ↗

Early-Onset Colorectal Cancer: From Genetic Discovery to Clinical InnovationSemantic proximity Read ↗

Epidemiology and biology of early onset colorectal cancerSemantic proximity Read ↗

Clinical Rather Than Genetic Factors Drive Prognosis in Early- Onset Colorectal Cancer: A Retrospective Cohort StudySemantic proximity Read ↗

Early Onset Colorectal Cancer: Molecular Underpinnings Accelerating Occurrence.Semantic proximity Read ↗

The Inherited and Familial Component of Early-Onset Colorectal Cancer.Semantic proximity Read ↗

Precision Oncology Insights into WNT Pathway Alterations in FOLFOX-Treated Early-Onset Colorectal Cancer in High-Risk PopulationsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.