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Article

Genomic Landscapes of Early-Onset Versus Average-Onset Colorectal Cancer Populations

28 Feb 2025

Abstract excerpt

Background: Rates of early-onset colorectal cancer (eoCRC), defined as disease diagnosed at <50 years of age, are increasing. The incidence and spectrum of somatic and pathogenic germline variants (PGV) in this population are not well understood. Methods: This cross-sectional study leveraged Tempus’ clinicogenomic database, including de-identified records of patients diagnosed with CRC between 2000–2022, to...

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PMID: 40075683
DOI: 10.3390/cancers17050836

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