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Comprehensive Genomic Landscapes in Early and Later Onset Colorectal Cancer

26 Jun 2019

Abstract excerpt

Abstract Purpose: The incidence rates of colorectal cancers are increasing in young adults. The objective of this study was to investigate genomic differences between tumor samples collected from younger and older patients with colorectal cancer. Experimental Design: DNA was extracted from 18,218 clinical specimens, followed by hybridization capture of 3,769 exons from 403 cancer-related genes and 47 introns of...

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PMID: 31243121
DOI: 10.1158/1078-0432.ccr-19-0899

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