Treatment Patterns and Clinical Outcomes Among Patients With Metastatic Prostate Cancer Harboring Homologous Recombination Repair Mutations.

doi:10.1016/j.clgc.2024.102080

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Article

Treatment Patterns and Clinical Outcomes Among Patients With Metastatic Prostate Cancer Harboring Homologous Recombination Repair Mutations.

Clinical genitourinary cancer - 1 Jun 2024

Bobbili Priyanka J, Ivanova Jasmina, Solit David B, Mettu Niharika B, McCall Shannon J, Dhawan Mallika, DerSarkissian Maral, Arondekar Bhakti, Chang Jane, Niyazov Alexander, Lee Jocelyn, Huq Risha, Green Michelle, Turski Michelle, Lam Phu, Muthukumar Aruna, Guo Tracy, Mohan Manasi, Zhang Adina, Duh Mei Sheng, Oh William K

Abstract excerpt

BACKGROUND: There is currently limited literature assessing the real-world treatment patterns and clinical outcomes of patients with metastatic castration-resistant prostate cancer (mCRPC) and homologous recombination repair (HRR) mutations. METHODS: Medical charts were abstracted for mCRPC patients with ≥ 1 of 12 HRR somatic gene alterations treated at US oncology centers participating in the American...

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PMID: 38653037
DOI: 10.1016/j.clgc.2024.102080

Genes

ATM
BRCA2
CDK12

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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