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Systematic Literature Review of the Epidemiology of Advanced Prostate Cancer and Associated Homologous Recombination Repair Gene Alterations.

The Journal of urology - 1 Apr 2021

Shore Neal, Oliver Louisa, Shui Irene, Gayle Alicia, Wong On-Ye, Kim Jeri, Payne Sarah, Amin Suvina, Ghate Sameer

Abstract excerpt

PURPOSE: To characterize the global epidemiology of metastatic castration-sensitive prostate cancer (mCSPC), nonmetastatic castration-resistant prostate cancer (nmCRPC) and metastatic castration-resistant prostate cancer (mCRPC). Additionally, to assess the prevalence of homologous recombination repair gene alterations (HRRm) and their prognostic impact in advanced disease setting. MATERIALS AND METHODS: A...

Topics

Biomarkers, Tumor
Circulating Tumor DNA
DNA Mutational Analysis
Disease Progression
Genetic Predisposition to Disease
Germ-Line Mutation
Humans
Male
Neoplasm Metastasis
Prevalence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Prognosis

Prostate-Specific Antigen

Prostatic Neoplasms, Castration-Resistant

Recombinational DNA Repair

Source

Identifiers

PMID: 33332152
DOI: 10.1097/JU.0000000000001570

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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