Article
Homologous Recombination Repair Gene Mutations in Prostate Cancer: Prevalence and Clinical Value.
Advances in therapy - 1 Jun 2024
Fan Yu, Liu Zhenhua, Chen Yuke, He Zhisong
Abstract excerpt
Despite advances in our understanding of the molecular landscape of prostate cancer and the development of novel biomarker-driven therapies, the prognosis of patients with metastatic prostate cancer that is resistant to conventional hormonal therapy remains poor. Data suggest that a significant proportion of patients with metastatic castration-resistant prostate cancer (mCRPC) have mutations in homologous...
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