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Article

The topological model of NS4B and its TMD3 in duck TMUV proliferation.

Poultry science - 1 Jun 2024

Jiang Bowen, Zhang Wei, He Yu, Wu Zhen, Wang Mingshu, Jia Renyong, Zhu Dekang, Liu Mafeng, Zhao Xinxin, Yang Qiao, Wu Ying, Zhang Shaqiu, Huang Juan, Ou Xumin, Sun Di, Cheng Anchun, Chen Shun

Abstract excerpt

Duck Tembusu virus (DTMUV) belongs to the Flaviviridae family and mainly infects ducks. Duck Tembusu virus genome encodes one polyprotein that undergoes cleavage to produce 10 proteins. Among these, NS4B, the largest transmembrane protein, plays a crucial role in the viral life cycle. In this study, we investigated the localization of NS4B and found that it is located in the endoplasmic reticulum, where it...

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Identifiers

PMID: 38652953
DOI: 10.1016/j.psj.2024.103727
PMCID: PMC11063511

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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