Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Single Mutation at Position 120 in the Envelope Protein Attenuates Tembusu Virus in Ducks.

Viruses - 22 Feb 2022

Yan Dawei, Wang Binbin, Shi Ying, Ni Xintao, Wu Xiaogang, Li Xuesong, Liu Xingpo, Wang Haiwang, Su Xin, Teng Qiaoyang, Yang Jianmei, Liu Qinfang, Li Zejun

Abstract excerpt

A live attenuated duck Tembusu virus (TMUV) vaccine FX2010-180P (180P) was successfully utilized to prevent TMUV infections in ducks in China. Compared with wild-type TMUV, 180P was highly attenuated and lost transmissibility in ducks. However, the mechanism of the attenuation of 180P remains poorly understood. To explore the key molecular basis of attenuation, chimeric and site mutant viruses in the background...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Line
Share to Ducks

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Flavivirus

Share to Mosquito-borne diseases and control

Share to Mutation

Share to Poultry Diseases

Share to Vaccines, Attenuated

Share to Viral Infections and Vectors

Source

Open in PubMed Open full text

Identifiers

PMID: 35336854
DOI: 10.3390/v14030447
PMCID: PMC8951291

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Single Mutation at Position 120 in the Envelope Protein Attenuates Tembusu Virus in Ducks.PMID 35336854Read ↗

A Single Mutation at Position 156 in the Envelope Protein of Tembusu Virus Is Responsible for Virus Tissue Tropism and Transmissibility in DucksSemantic proximity Read ↗

Basic Amino Acid Substitution at Residue 367 of the Envelope Protein of Tembusu Virus Plays a Critical Role in Pathogenesis.Semantic proximity Read ↗

Structural, antigenic, and evolutionary characterizations of the envelope protein of newly emerging Duck Tembusu Virus.Semantic proximity Read ↗

The topological model of NS4B and its TMD3 in duck TMUV proliferation.Semantic proximity Read ↗

Amino Acid Substitutions in NS5 Contribute Differentially to Tembusu Virus Attenuation in Ducklings and Cell Cultures.Semantic proximity Read ↗

Glycosylation on envelope glycoprotein of duck Tembusu virus affects virus replication in vitro and contributes to the neurovirulence and pathogenicity in vivoSemantic proximity Read ↗

Evolution of Tembusu Virus in Ducks, Chickens, Geese, Sparrows, and Mosquitoes in Northern China.Semantic proximity Read ↗

The Evolution, Genomic Epidemiology, and Transmission Dynamics of Tembusu VirusSemantic proximity Read ↗

Complete Genome Sequence of a Novel Flavivirus, Duck Tembusu Virus, Isolated from Ducks and Geese in ChinaSemantic proximity Read ↗

Oral Vaccination with a DNA Vaccine Encoding Capsid Protein of Duck Tembusu Virus Induces Protection ImmunitySemantic proximity Read ↗

Long-term passage of duck Tembusu virus in BHK-21 cells generates a completely attenuated and immunogenic population with increased genetic diversity.Semantic proximity Read ↗

The presence of duck Tembusu virus in Thailand since 2007: A retrospective studySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.