TRIM14 restricts tembusu virus infection through degrading viral NS1 protein and activating type I interferon signaling

Abstract excerpt

Tembusu virus (TMUV), an emerging avian orthoflavivirus, causes severe economic losses due to egg-drop syndrome and fatal encephalitis in domestic waterfowl. To combat this threat, the host immune system plays a crucial role in controlling and eliminating TMUV infection. Understanding the mechanisms of this immune response is thus vital for developing effective strategies against the virus. In this study, we...

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• interferon and immune responses
• Mosquito-borne diseases and control
• Viral Infections and Vectors