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Article

Clonal hematopoiesis of indeterminate potential in patients with immunoglobulin light-chain AL amyloidosis.

Blood advances - 9 Jul 2024

Lopedote Paolo, Evans Benjamin, Marchetti Alfredo, Chen Tianzeng, Moscvin Maria, Boullt Samuel, Bolli Niccolò, Bianchi Giada

Abstract excerpt

ABSTRACT: Immunoglobulin light-chain (AL) amyloidosis is characterized by the deposition of misfolded monoclonal free light chains, with cardiac complications accounting for patient mortality. Clonal hematopoiesis of indeterminate potential (CHIP) has been associated with worse cardiovascular outcomes in the general population. Its significance in AL amyloidosis remains unclear. We collected clinical information...

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Identifiers

PMID: 38652890
DOI: 10.1182/bloodadvances.2024012840
PMCID: PMC11259929

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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