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Article

Clonal hematopoiesis of indeterminate potential and risk of immune thrombocytopenia.

Journal of internal medicine - 1 Jun 2025

Liu Qianwei, Wästerlid Tove, Smedby Karin E, Xue Huiwen, Boberg Erik, Fang Fang, Liu Xinyuan

Abstract excerpt

BACKGROUND: Clonal hematopoiesis of indeterminate potential (CHIP) might contribute to the pathogenesis of immune thrombocytopenia (ITP) through immune dysfunction or impairment of megakaryopoiesis and platelet formation. However, little is known about subsequent risk of ITP among individuals with CHIP. OBJECTIVE: To investigate the risk of ITP among individuals with CHIP. METHODS: We investigated the association...

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Source

Identifiers

PMID: 40302051
DOI: 10.1111/joim.20092

Genes

JAK2
SRSF2
DNMT3A
TET2
ASXL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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