Article
LncRNA RP11-301G19.1 is required for the maintenance of vascular smooth muscle cell contractile phenotype via sponging miR-17-5P/ATOH8 axis.
IUBMB life - 1 Sept 2024
Hao Shuning, Zuo Feifei, Zhang Hongmin, Wang Ying, Huang Liwen, Ma Fenghui, Song Tiefeng, Zhang Tongcun, Ren Xuejun, Wang Nan
Abstract excerpt
Long noncoding RNAs (LncRNAs) play essential roles in regulating gene expression in various biological processes. However, the function of lncRNAs in vascular smooth muscle cell (VSMC) transformation remains to be explained. In this work, we discover that a new bone marrow protein (BMP) signaling target, lncRNA RP11-301G19.1, is significantly induced in BMP7-treated VSMCs through lncRNA microarray analysis....
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