Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Circ_0021155 can participate in the phenotypic transformation of human vascular smooth muscle cells via the miR-4459/TRPM7 axis.

Biochemical and biophysical research communications - 19 Nov 2022

Lin Jinghan, Liu Chang, Xu Jing, Li Shuang, Dai Dawei, Zhang Liming, Yonghui Pan

Abstract excerpt

The phenotypic transformation of vascular smooth muscle cells (VSMCs) plays a key role in the pathological process of atherosclerosis (AS), and TRPM7 is involved in this process. In this study, we verified whether circRNAs participate in the phenotypic transformation of VSMCs by regulating TRPM7 in AS. The RNA-sequencing data of atherosclerosis were downloaded and analysed from the GEO database. Only...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Actins
Share to Atherosclerosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Movement

Share to MicroRNAs

Share to Muscle, Smooth, Vascular

Share to Protein Serine-Threonine Kinases

Share to RNA, Circular

Share to TRPM Cation Channels

Source

Identifiers

PMID: 36155059
DOI: 10.1016/j.bbrc.2022.08.065

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Circ_0021155 can participate in the phenotypic transformation of human vascular smooth muscle cells via the miR-4459/TRPM7 axis.PMID 36155059Read ↗

Exosomes: mediators regulating the phenotypic transition of vascular smooth muscle cells in atherosclerosis.Semantic proximity Read ↗

OxLDL-Stimulated Macrophages Transmit Exosomal MicroRNA-320b to Aggravate Viability, Invasion, and Phenotype Switching via Regulating PPARGC1A-Mediated MEK/ERK Pathway in Proatherogenic Vascular Smooth Muscle Cells.Semantic proximity Read ↗

Canonical Transient Receptor Potential Channels and Vascular Smooth Muscle Cell PlasticitySemantic proximity Read ↗

MicroRNA-22-3p Restrains the Proliferation, Phenotypic Transformation, and Migration of Vascular Smooth Muscle Cells by Manipulating TOMM40.Semantic proximity Read ↗

MicroRNA regulation of phenotypic transformations in vascular smooth muscle: relevance to vascular remodeling.Semantic proximity Read ↗

LncRNA MFRL regulates the phenotypic switch of vascular smooth muscle cells to attenuate arterial remodeling by encoding a novel micropeptide MFRLP.Semantic proximity Read ↗

MTMR7 suppresses the phenotypic switching of vascular smooth muscle cell and vascular intimal hyperplasia after injury via regulating p62/mTORC1-mediated glucose metabolismSemantic proximity Read ↗

Metformin Inhibits the Phenotypic Transformation of Aortic Vascular Smooth Muscle Cells Induced by Hyperglycemia Through Regulation of the Mir-21-mediated PTEN/pAKT/Egr-1 PathwaySemantic proximity Read ↗

MicroRNA regulation of smooth muscle gene expression and phenotype.Semantic proximity Read ↗

An update on the phenotypic switching of vascular smooth muscle cells in the pathogenesis of atherosclerosis.Semantic proximity Read ↗

Differential expression and bioinformatics analysis of circRNA in PDGF-BB-induced vascular smooth muscle cellsSemantic proximity Read ↗

The long noncoding RNA uc003pxg.1 interacts with miR-339-5p to promote TGF-β1 expression and vascular endothelial cell proliferation, migration and angiogenesis in coronary heart diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.