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Article

A novel mutation in hERG gene associated with azithromycin-induced acquired long QT syndrome.

Molecular biology reports - 16 Apr 2024

Cheng Yun-Jiu, Wu Yang, Wei Hui-Qiang, Liao Yi-Jian, Qu Li-Ping, Pan Yue-Han, Liu Li-Juan, Bi Wen-Tao

Abstract excerpt

BACKGROUND: Mutations in human ether-à-go-go-related gene (hERG) potassium channels are closely associated with long QT syndrome (LQTS). Previous studies have demonstrated that macrolide antibiotics increase the risk of cardiovascular diseases. To date, the mechanisms underlying acquired LQTS remain elusive. METHODS: A novel hERG mutation I1025N was identified in an azithromycin-treated patient with acquired long...

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Identifiers

PMID: 38625436
DOI: 10.1007/s11033-024-09421-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A novel mutation in hERG gene associated with azithromycin-induced acquired long QT syndrome.PMID 38625436Read ↗

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