Article
Comprehensive characterization of genomic features and clinical outcomes following targeted therapy and secondary cytoreductive surgery in OCCC: a single center experience.
Journal of gynecologic oncology - 1 Sept 2024
Wijaya Silvana Talisa, Ngoi Natalie Yl, Loh Jerold Wz, Tan Tuan Zea, Lim Diana, Khan Irfan Sagir, Thian Yee Liang, Lai Alexa, Ang Bertrand Wl, Tong Pearl, Ng Joseph, Low Jeffrey Jh, Ilancheran Arunachalam, Lim Siew Eng, Lim Yi Wan, Tan David Sp
Abstract excerpt
OBJECTIVE: Ovarian clear cell carcinoma (OCCC) is associated with chemoresistance. Limited data exists regarding the efficacy of targeted therapies such as immune checkpoint inhibitors (ICI) and bevacizumab, and the role of secondary cytoreductive surgery (SCS). METHODS: We retrospectively analyzed genomic features and treatment outcomes of 172 OCCC patients treated at our institution from January 2000 to May...
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