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Prediabetes phenotypes: can aetiology and risk profile guide lifestyle strategies for diabetes prevention?

Expert review of endocrinology & metabolism - 1 Sept 2025

Poppitt Sally D, Miles-Chan Jennifer, Silvestre Marta P

Abstract excerpt

INTRODUCTION: Type 2 diabetes (T2D) continues to worsen globally alongside rise in obesity. Asymptomatic dysglycaemia, which precedes T2D, provides opportunities to identify those at risk and target prevention but prediabetes is highly variable. Not all with overweight develop dysglycaemia and not all with dysglycaemia are overweight. Important is the deposition of ectopic lipids in the pancreas, liver, and...

Read the complete abstract on PubMed

Topics

Humans
Prediabetic State
Diabetes Mellitus, Type 2
Phenotype
Life Style
Risk Factors
Blood Glucose

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 40650958
DOI: 10.1080/17446651.2025.2532559

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