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Article

Extracellular Vesicles from Highly Metastatic Osteosarcoma Cells Induce Pro-Tumorigenic Macrophage Phenotypes.

Advanced biology - 1 Jun 2024

Griffin Katherine H, Mizenko Rachel R, Arun Vishalakshi, Carney Randy P, Leach J Kent

Abstract excerpt

Metastasis is the principal factor in poor prognosis for individuals with osteosarcoma (OS). Understanding the events that lead to metastasis is critical to develop better interventions for this disease. Alveolar macrophages are potentially involved in priming the lung microenvironment for OS metastasis, yet the mechanisms involved in this process remain unclear. Since extracellular vesicles (EVs) are a known...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38596830
DOI: 10.1002/adbi.202300577
PMCID: PMC11178448

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