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Article

Rab37 in lung cancer mediates exocytosis of soluble ST2 and thus skews macrophages toward tumor-suppressing phenotype.

International journal of cancer - 1 Oct 2018

Tzeng Hong-Tai, Su Ching-Chin, Chang Chih-Peng, Lai Wu-Wei, Su Wu-Chou, Wang Yi-Ching

Abstract excerpt

Interplay between cancer epithelial cells and the surrounding immune cells shape the tumor microenvironment to promote cancer progression. Tumor-associated macrophages are well recognized for their roles in cancer progression. Accumulating evidence also indicates implication of Rab small GTPase-mediated exocytosis in tumorigenesis. However, the mechanism for Rab-mediated exocytosis in regulation of macrophage...

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Identifiers

PMID: 29717487
DOI: 10.1002/ijc.31569

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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