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Article

Influence of Canine Macrophage-derived Extracellular Vesicles on Apoptosis in Canine Melanoma and Osteosarcoma Cell Lines.

Anticancer research - 1 Feb 2021

Lee Kyung-Mi, An Ju-Hyun, Yang Se-Jin, Park Su-Min, Lee Jeong-Hwa, Chae Hyung-Kyu, Song Woo-Jin, Youn Hwa-Young

Abstract excerpt

BACKGROUND/AIM: The purpose of this study was to evaluate the effect of extracellular vesicles derived from canine M1-polarized macrophages (M1EVs) on canine tumor cells, such as D17 (osteosarcoma cells) and LMeC (melanoma cells). MATERIALS AND METHODS: Protein expression was determined by western blot analysis. Gene expression was determined by RT-qPCR. In addition, cell apoptosis was analyzed by Annexin V/PI...

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PMID: 33517276
DOI: 10.21873/anticanres.14823

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