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Article

Tumor-associated vacuolar ATPase subunit promotes tumorigenic characteristics in macrophages.

Oncogene - 4 Dec 2014

Katara G K, Jaiswal M K, Kulshrestha A, Kolli B, Gilman-Sachs A, Beaman K D

Abstract excerpt

Macrophage polarization contributes to distinct human pathologies. In tumors, a polarized M2 phenotype called tumor-associated macrophages (TAMs) are associated with promotion of invasion and angiogenesis. In cancer cells, vacuolar ATPase (V-ATPase), a multi-subunit enzyme, is expressed on the pl...

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Share to Gene Expression Regulation, Enzymologic
Share to Lymphocyte Activation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Inbred BALB C

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Share to Neovascularization, Pathologic

Share to Vacuolar Proton-Translocating ATPases

Source

Identifiers

PMID: 24362525
DOI: 10.1038/onc.2013.532

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24362525-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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