Article
fastDFE: Fast and Flexible Inference of the Distribution of Fitness Effects.
Molecular biology and evolution - 3 May 2024
Sendrowski Janek, Bataillon Thomas
Abstract excerpt
Estimating the distribution of fitness effects (DFE) of new mutations is of fundamental importance in evolutionary biology, ecology, and conservation. However, existing methods for DFE estimation suffer from limitations, such as slow computation speed and limited scalability. To address these issues, we introduce fastDFE, a Python-based software package, offering fast, and flexible DFE inference from...
Topics
- Software
- Genetic Fitness
- Mutation
- Models, Genetic