Article
ST2 and IL-33 polymorphisms and the development of childhood asthma: a prospective birth cohort study in Finnish children.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica - 1 Jul 2024
Teräsjärvi Johanna T, Toivonen Laura, Mertsola Jussi, Peltola Ville, He Qiushui
Abstract excerpt
The ST2/IL-33 signaling pathway has an important role in the host inflammatory response. Here we aimed to study the association of ST2 and IL-33 polymorphisms with serum soluble (s) ST2 and IL-33 concentrations in healthy Finnish children and, in addition, their association with childhood asthma. In total, 146 children were followed from birth to the age 7 years for the development of asthma. Single-nucleotide...
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