Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Investigations into the role of ST2 in acute asthma in children.

Tissue antigens - 1 Mar 2009

Ali M, Zhang G, Thomas W R, McLean C J, Bizzintino J A, Laing I A, Martin A C, Goldblatt J, Le Souëf P N, Hayden C M

Abstract excerpt

The ST2 gene is a member of the interleukin-1 receptor family and is located on chromosome 2q12, an area of the genome that has been associated with asthma. The soluble product of the ST2 gene, serum ST2 (sST2), has previously been shown to be elevated in adult asthmatic patients. This study investigated the potential role of ST2 in children with acute asthma. Children aged 2-16 years (n = 186) were recruited on...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Disease
Share to Asthma
Share to Child

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Child, Preschool

Share to Haplotypes

Share to Interleukin-1 Receptor-Like 1 Protein

Share to Polymorphism, Genetic

Share to Receptors, Cell Surface

Source

Identifiers

PMID: 19254249
DOI: 10.1111/j.1399-0039.2008.01185.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Investigations into the role of ST2 in acute asthma in children.PMID 19254249Read ↗

ST2 and IL-33 polymorphisms and the development of childhood asthma: a prospective birth cohort study in Finnish children.Semantic proximity Read ↗

IL1RL1 asthma risk variants regulate airway type 2 inflammation.Semantic proximity Read ↗

Functional SNPs in the distal promoter of the ST2 gene are associated with atopic dermatitis.Semantic proximity Read ↗

Phenotypic and genotypic association of epithelial IL1RL1 to human TH2-like asthma.Semantic proximity Read ↗

Common genetic variation at the IL1RL1 locus regulates IL-33/ST2 signaling.Semantic proximity Read ↗

ST2 Protein in Heart Disease: From Discovery to Mechanisms and Prognostic ValueSemantic proximity Read ↗

The single nucleotide polymorphism CRTh2 rs533116 is associated with allergic asthma and increased expression of CRTh2.Semantic proximity Read ↗

The role of ST2 and ST2 genetic variants in schistosomiasis.Semantic proximity Read ↗

Association analysis of cysteinyl-leukotriene receptor 2 (CYSLTR2) polymorphisms with aspirin intolerance in asthmatics.Semantic proximity Read ↗

A functional variant in ST2 gene is associated with risk of hypertension via interfering MiR-202-3p.Semantic proximity Read ↗

The role of GATA2 in the expression of the soluble decoy receptor ST2/IL1RL1 in human and mouse mast cellsSemantic proximity Read ↗

A functional IL1RL1 variant regulates corticosteroid-induced sST2 expression in ulcerative colitis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.