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Article

Synergizing the interaction of single nucleotide polymorphisms with dosiomics features to build a dual-omics model for the prediction of radiation pneumonitis.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology - 1 Jul 2024

Liang Bin, Lu Xiaotong, Liu Lipin, Dai Jianrong, Wang Luhua, Bi Nan

Abstract excerpt

OBJECTIVE: Radiation pneumonitis (RP) is the major dose-limiting toxicity of thoracic radiotherapy. This study aimed to developed a dual-omics (single nucleotide polymorphisms, SNP and dosiomics) prediction model for symptomatic RP. MATERIALS AND METHODS: The potential SNPs, which are of significant difference between the RP grade ≥ 3 group and the RP grade ≤ 1 group, were selected from the whole exome sequencing...

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PMID: 38548115
DOI: 10.1016/j.radonc.2024.110261

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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