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A two-stage genome-wide association study of radiation-induced acute toxicity in head and neck cancer

27 Nov 2021

Abstract excerpt

Abstract Background Most head and neck cancer (HNC) patients receive radiotherapy (RT) and develop toxicities. This genome-wide association study (GWAS) was designed to identify single nucleotide polymorphisms (SNPs) associated with common acute radiation-induced toxicities (RITs) in an HNC cohort. Methods A two-stage GWAS was performed in 1279 HNC patients treated with RT and prospectively scored for mucositis,...

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Effects of Radiation Exposure
Head and Neck Cancer Studies
Oral health in cancer treatment

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34838041
DOI: 10.1186/s12967-021-03145-1

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