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K33 only mutant ubiquitin augments bone marrow-derived dendritic cell-mediated CTL priming via PI3K-Akt pathway.

Immunology - 1 Jul 2024

Liang Yi Yun, Liao Xiao Yan, Jia Jun Jun, Yin Yi Zhen, Zhang Yue Hua, Gao Feng Guang

Abstract excerpt

To explore the effect of K33 only mutant ubiquitin (K33O) on bone marrow-derived dendritic cells' (BMDCs') maturity, antigen uptake capability, surface molecule expressions and BMDC-mediated CTL priming, and further investigate the role of PI3K-Akt engaged in K33O-increased BMDC maturation, antigen uptake and presentation, surface molecule expressions and BMDC-based CTL priming. BMDCs were conferred K33O and...

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Androstadienes
Antigen Presentation
B7-2 Antigen
Chromones
Lymphocyte Culture Test, Mixed

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38547355
DOI: 10.1111/imm.13787

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