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Article

Flow cytometry-assisted analysis of phenotypic maturation markers on an immortalized dendritic cell line.

Methods in cell biology - 1 Jan 2024

Campia Ginevra, Beltrán-Visiedo Manuel, Soler-Agesta Ruth, Sato Ai, Bloy Norma, Zhao Liwei, Liu Peng, Kepp Oliver, Kroemer Guido, Galluzzi Lorenzo, Galassi Claudia

Abstract excerpt

Dendritic cells (DCs), and especially so conventional type I DCs (cDC1s), are fundamental regulators of anticancer immunity, largely reflecting their superior ability to engulf tumor-derived material and process it for cross-presentation on MHC Class I molecules to CD8+ cytotoxic T lymphocytes (CTLs). Thus, investigating key DC functions including (but not limited to) phagocytic capacity, expression of...

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PMID: 39393881
DOI: 10.1016/bs.mcb.2024.05.008

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