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Article

Phenotypic Profiling Reveals that Candida albicans Opaque Cells Represent a Metabolically Specialized Cell State Compared to Default White Cells.

mBio - 22 Nov 2016

Ene Iuliana V, Lohse Matthew B, Vladu Adrian V, Morschhäuser Joachim, Johnson Alexander D, Bennett Richard J

Abstract excerpt

The white-opaque switch is a bistable, epigenetic transition affecting multiple traits in Candida albicans including mating, immunogenicity, and niche specificity. To compare how the two cell states respond to external cues, we examined the fitness, phenotypic switching, and filamentation properties of white cells and opaque cells under 1,440 different conditions at 25°C and 37°C. We demonstrate that white and...

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Identifiers

PMID: 27879329
DOI: 10.1128/mBio.01269-16
PMCID: PMC5120136

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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