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Cross-ancestry genetic architecture and prediction for cholesterol traits.

Human genetics - 1 May 2024

Momin Md Moksedul, Zhou Xuan, Hyppönen Elina, Benyamin Beben, Lee S Hong

Abstract excerpt

While cholesterol is essential, a high level of cholesterol is associated with the risk of cardiovascular diseases. Genome-wide association studies (GWASs) have proven successful in identifying genetic variants that are linked to cholesterol levels, predominantly in white European populations. However, the extent to which genetic effects on cholesterol vary across different ancestries remains largely unexplored....

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PMID: 38536467
DOI: 10.1007/s00439-024-02660-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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