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Separating distant recurrences from second primaries in head and neck squamous cell carcinomas - A DAHANCA group analysis on paired tumor samples.

Head & neck - 1 Oct 2024

Kjems Julie, Lilja-Fischer Jacob Kinggaard, Friborg Jeppe, Tramm Trine, Overgaard Jens

Abstract excerpt

BACKGROUND: In head and neck squamous cell carcinomas (HNSCC), there is no clinically available method to separate distant metastases (DMs) from SCC secondary primary tumors. The study aimed to assess the genetic relationship in paired tumor samples. METHODS: Patients with pairs of solid biopsies from the primary HNSCC and suspected DMs were identified (2007-2017). Targeted next-generation sequencing of 22 genes...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38528796
DOI: 10.1002/hed.27750

Genes

TP53

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