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Observing G4 formation and its resolution by Pif1 in real time by manipulation under magnetic tweezers.

Methods in enzymology - 1 Jan 2024

Valle-Orero Jessica, Rieu Martin, Allemand Jean-François, Bujaa Dulamkhuu, Joubert Alexandra, Tran Phong Lan Thao, Croquette Vincent, Boulé Jean-Baptiste

Abstract excerpt

G-quadruplexes (G4s) are nucleic acids secondary structures that may form in guanine-rich sequences, either intra or inter-molecularly. Ability of a primary sequence to form a G4 can be predicted computationally with an improving accuracy as well as tested in bulk using biophysical measurements. As a result, G4 density maps have been devised for a large number of genomes from all life kingdoms. Experimental...

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PMID: 38521583
DOI: 10.1016/bs.mie.2023.12.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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