Article
Association of lipid-modifying therapy with risk of obstructive sleep apnea: A drug-target mendelian randomization study.
Toxicology and applied pharmacology - 1 Apr 2024
Zou Juanjuan, Qi Shengnan, Sun Xiaojing, Zhang Yijing, Wang Yan, Li Yanzhong, Zhao Ze-Hua, Lei Dapeng
Abstract excerpt
BACKGROUND: Obstructive sleep apnea (OSA) is considered to be an important contributor of dyslipidemia. However, there lacks observational studies focusing on the potential effect of lipid management on OSA risk. Thus, we aimed to investigate the genetic association of lipid-modifying therapy with risk of OSA. METHODS: A drug-target mendelian randomization (MR) study using both cis-variants and cis-expression...
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