Mendelian randomization reveals no associations of genetically-predicted obstructive sleep apnea with the risk of type 2 diabetes, nonalcoholic fatty liver disease, and coronary heart disease

Abstract excerpt

Background Obstructive sleep apnea (OSA) has been reported to affect cardiometabolic diseases. However, whether such association is causal is still unknown. Here, we attempt to explore the effect of OSA on type 2 diabetes (T2D), nonalcoholic fatty liver disease (NAFLD) and coronary heart disease (CHD). Methods Genetic variants associated with OSA were requested from a published genome-wide association study...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cardiovascular Disease and Adiposity
• Share to Genetic Associations and Epidemiology
• Share to Obstructive Sleep Apnea Research