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Article

Mendelian Randomization Analysis of ITGA2 and ECM1 in Obstructive Sleep Apnea: Genetic and Tissue-Specific Evidence

2025-04-17

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<title>Abstract</title> <p>Purpose Obstructive sleep apnea syndrome (OSA) has a complex etiology and lacks targeted therapies. This study employs Mendelian randomization (MR) to identify druggable targets causally associated with OSA risk, elucidate their molecular mechanisms, and guide the development of precision treatments. Methods Cis-eQTL data for drug-target genes were extracted from the eQTLGen database...

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Literature Corpus work
3f119b00-d363-5fac-b843-8c9d4a413d2d
DOI
10.21203/rs.3.rs-6277320/v1
Open publication

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