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Article

Effect of inflammatory cytokines and plasma metabolome on OSA: a bidirectional two- sample Mendelian randomization study and mediation analysis.

Frontiers in immunology - 1 Jan 2024

Sun Xin, Wang Congying, He Yuheng, Chen Kun, Miao YingZhang

Abstract excerpt

Background: Obstructive sleep apnea (OSA) is a common sleep disorder. Inflammatory factors and plasma metabolites are important in assessing its progression. However, the causal relationship between them and OSA remains unclear, hampering early clinical diagnosis and treatment decisions. Methods: We conducted a large-scale study using data from the FinnGen database, with 43,901 cases and 366,484 controls for our...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39351220
DOI: 10.3389/fimmu.2024.1416870
PMCID: PMC11439640

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