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Plasma homocysteine level, estradiol level, and brain atrophy: a Mendelian randomization study

1 Mar 2024

Abstract excerpt

OBJECTIVES: Observational studies link elevated plasma homocysteine (Hcy) with vascular disease. Our aim was to assess the gender difference in the association between the plasma tHcy level and brain atrophy and identify the possible influencer. We employed Mendelian randomization (MR) to explore the causal relationship between plasma tHcy level, estradiol level, and brain atrophy. METHODS: A total of 687...

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PMID: 38517173
DOI: 10.1093/cercor/bhae112

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