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The Effects of Plasma Homocysteine Level on the Risk of Three Major Psychiatric Disorders: A Mendelian Randomization Study

21 Mar 2022

Abstract excerpt

Background Higher homocysteine (Hcy) level has been suggested to be associated with major psychiatric disorders (MPDs), such as schizophrenia (SCZ), bipolar disorder (BD), and major depressive disorder (MDD). We investigated the causal relationships between plasma Hcy level and MPDs risks using the Mendelian randomization (MR) method. Methods We selected 18 loci associated with plasma Hcy level from a large-scale...

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PMID: 35386526
DOI: 10.3389/fpsyt.2022.841429

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