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Homocysteine, B vitamins, and cardiovascular disease: a Mendelian randomization study

22 Apr 2021

Abstract excerpt

Abstract Background Whether a modestly elevated homocysteine level is causally associated with an increased risk of cardiovascular disease remains unestablished. We conducted a Mendelian randomization study to assess the associations of circulating total homocysteine (tHcy) and B vitamin levels with cardiovascular diseases in the general population. Methods Independent single nucleotide polymorphisms associated...

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PMID: 33888102
DOI: 10.1186/s12916-021-01977-8

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