Article
Pattern formation by dynamically interacting network motifs.
Proceedings of the National Academy of Sciences of the United States of America - 3 Mar 2009
Lembong Jessica, Yakoby Nir, Shvartsman Stanislav Y
Abstract excerpt
Systematic validation of pattern formation mechanisms revealed by molecular studies of development is essentially impossible without mathematical models. Models can provide a compact summary of a large number of experiments that led to mechanism formulation and guide future studies of pattern formation. Here, we realize this program by analyzing a mathematical model of epithelial patterning by the highly...
Topics
- Animals
- Body Patterning
- Drosophila melanogaster
- Embryo, Nonmammalian
- Gene Expression Regulation, Developmental
- Imaging, Three-Dimensional
- Models, Biological
- Mutation