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Article

The Association between Inefficient Repair of DNA Double-Strand Breaks and Common Polymorphisms of the HRR and NHEJ Repair Genes in Patients with Rheumatoid Arthritis.

International journal of molecular sciences - 23 Feb 2024

Galita Grzegorz, Sarnik Joanna, Brzezinska Olga, Budlewski Tomasz, Poplawska Marta, Sakowski Sebastian, Dudek Grzegorz, Majsterek Ireneusz, Makowska Joanna, Poplawski Tomasz

Abstract excerpt

Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation affecting up to 2.0% of adults around the world. The molecular background of RA has not yet been fully elucidated, but RA is classified as a disease in which the genetic background is one of the most significant risk factors. One hallmark of RA is impaired DNA repair observed in patient-derived peripheral blood mononuclear...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38473866
DOI: 10.3390/ijms25052619
PMCID: PMC10932168

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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