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Genetic polymorphisms in homologous recombination repair genes in healthy Slovenian population and their influence on DNA damage

1 Jan 2012

Abstract excerpt

BACKGROUND: Homologous recombination (HR) repair is an important mechanism involved in repairing double-strand breaks in DNA and for maintaining genomic stability. Polymorphisms in genes coding for enzymes involved in this pathway may influence the capacity for DNA repair. The aim of this study was to select tag single nucleotide polymorphisms (SNPs) in specific genes involved in HR repair, to determine their...

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PMID: 22933979
DOI: 10.2478/v10019-012-0001-7

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